Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 9/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190019 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9190022 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9398421 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9398294 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9188492 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9188498 | 0.84 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL7767059 | 0.83 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL9620739 | 0.82 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9620737 | 0.82 | DAO (0.40) | DAOTRPV4KCNJ1KCNH2AR | |
| SCHEMBL9621201 | 0.81 | DAO (0.39) | DAOTRPV4KCNJ1KCNH2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |