Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117546 | 0.86 | NPY5R (0.46) | ALDH1A1KDM4EKMT2AL3MBTL1EPHX1 | |
| SCHEMBL5327739 | 0.84 | KDM4E (0.50) | KDM4EKMT2AL3MBTL1CA1CA2 | |
| SCHEMBL5327734 | 0.84 | KDM4E (0.50) | KDM4EKMT2AL3MBTL1CA1CA2 | |
| SCHEMBL7765665 | 0.82 | ANPEP (0.64) | KDM4EANPEPGSK3B | |
| SCHEMBL31203452 | 0.81 | CYP1A2 (0.54) | ALDH1A1EPHX1NPY5RCA1CA2 | |
| SCHEMBL8349352 | 0.80 | CA1 (0.47) | ALDH1A1KDM4EKMT2AL3MBTL1CA1 | |
| SCHEMBL6033439 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AL3MBTL1EPHX1 | |
| SCHEMBL6033443 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AL3MBTL1EPHX1 | |
| SCHEMBL2928021 | 0.79 | MEN1 (0.53) | ALDH1A1KMT2ACA1CA2ANPEP | |
| Hydrochloric Acid SCHEMBL10603453 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EKMT2AL3MBTL1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |