Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345990 | 0.91 | CA1 (0.46) | CA1CA2CXCR3SIRT5HDAC1 | |
| SCHEMBL8346795 | 0.91 | KDM4E (0.45) | CA1CA2HSD17B10CXCR3NTMT1 | |
| SCHEMBL7759044 | 0.81 | NTMT1 (0.58) | HSD17B10NTMT1HDAC1HDAC4HDAC2 | |
| SCHEMBL8343138 | 0.81 | NTMT1 (0.58) | HSD17B10NTMT1HDAC1HDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL7763503 | 0.81 | NTMT1 (0.57) | HSD17B10NTMT1HDAC1HDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL8349180 | 0.81 | NTMT1 (0.57) | HSD17B10NTMT1HDAC1HDAC4HDAC2 | |
| SCHEMBL7762702 | 0.80 | ALDH1A1 (0.49) | CA1CA2HSD17B10ALDH1A1CTSS | |
| SCHEMBL8345432 | 0.79 | HDAC1 (0.51) | SIRT5HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL8349755 | 0.79 | HDAC1 (0.50) | SIRT5HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL8349145 | 0.78 | HDAC1 (0.49) | SIRT5HDAC1HDAC4HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |