Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.51 |
| ▸ | MGAM | O43451 | 8/20 | 0.51 |
| ▸ | SI | P14410 | 8/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762915 | 0.86 | MGAM (0.55) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7822007 | 0.83 | MGAM (0.59) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7759238 | 0.83 | MGAM (0.51) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL3582297 | 0.83 | AURKB (0.64) | AURKAAURKB | |
| SCHEMBL6581301 | 0.80 | AURKB (0.47) | HPSEAURKAAURKB | |
| SCHEMBL7765849 | 0.79 | MGAM (0.54) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7761994 | 0.77 | CYP1A2 (0.52) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7764169 | 0.77 | MGAM (0.52) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7763627 | 0.76 | GAA (0.51) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL7763616 | 0.76 | ACHE (0.64) | GAAMGAMSIMGAM2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| EP-1127052-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026192-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |