Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 9/20 | 0.68 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77442 | 0.84 | KMT2A (0.68) | ROCK1ROCK2KMT2AALDH1A1MEN1 | |
| SCHEMBL91529 | 0.84 | ROCK1 (0.70) | ROCK1ROCK2KMT2AALDH1A1MEN1 | |
| SCHEMBL13528022 | 0.83 | KMT2A (0.50) | ROCK1ROCK2KMT2AALDH1A1MEN1 | |
| SCHEMBL2558208 | 0.81 | ROCK1 (1.00) | ROCK1ROCK2 | |
| Hydrochloric Acid SCHEMBL2559843 | 0.81 | ROCK1 (0.98) | ROCK1ROCK2 | |
| SCHEMBL77074 | 0.78 | MAPK1 (0.69) | ROCK1ROCK2KMT2AALDH1A1MEN1 | |
| SCHEMBL77071 | 0.78 | KMT2A (0.69) | ROCK1ROCK2KMT2AALDH1A1MEN1 | |
| SCHEMBL2553941 | 0.78 | ROCK1 (0.93) | ROCK1ROCK2 | |
| SCHEMBL3815151 | 0.76 | ALDH1A1 (0.72) | ROCK2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL77064 | 0.75 | KMT2A (0.70) | ROCK1ROCK2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ROCK1 2709/4885ROCK2 2794/4885KMT2A 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.