Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MMP13 | P45452 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | ANPEP | P15144 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853495 | 0.92 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL23771131 | 0.91 | ALDH1A1 (0.65) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL14088778 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL5759180 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL660541 | 0.88 | MMP13 (0.70) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL2931410 | 0.88 | MMP13 (0.70) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL17905725 | 0.87 | EPHX2 (0.69) | ALDH1A1HTTSMN1; SMN2MMP13EPHX2 | |
| SCHEMBL18175810 | 0.87 | ALDH1A1 (0.68) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| SCHEMBL30104666 | 0.87 | ALDH1A1 (0.68) | ALDH1A1HTTSMN1; SMN2MMP13LMNA | |
| Hydrochloric Acid SCHEMBL29194804 | 0.87 | MMP13 (0.68) | ALDH1A1HTTSMN1; SMN2MMP13LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479370-B1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | USA (US) | 2009-07-08 | — | — | EP | disclosed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1280495-B1 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | US AGRICULTURE (US) | 2006-11-22 | — | — | EP | disclosed |
| US-7053243-B2 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1479370-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | The United States of America (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | SECRETARY OF AGRICULTURE | 2004-02-12 | — | — | US | disclosed |
| US-6653505-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-11-25 | — | — | US | disclosed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | disclosed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | disclosed |
| EP-1280495-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | Abbott, Thomas, P. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2001-12-27 | — | — | US | disclosed |
| WO-2001085681-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | THE FANNING CORPORATION (US) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885HTT 1952/4885SMN1; SMN2 2443/4885 |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885HTT 1952/4885SMN1; SMN2 2443/4885 |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885HTT 1952/4885SMN1; SMN2 2443/4885 |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885HTT 1952/4885SMN1; SMN2 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.