Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 9/20 | 0.70 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237515 | 0.84 | ROCK1 (0.67) | ROCK1ROCK2ATG4B | |
| SCHEMBL77629 | 0.84 | ROCK1 (0.68) | ROCK1ROCK2MAPTALDH1A1MEN1 | |
| SCHEMBL91397 | 0.84 | ROCK2 (0.62) | ROCK1ROCK2MEN1LMNAKMT2A | |
| SCHEMBL13528624 | 0.83 | ALDH1A1 (0.47) | ROCK1ROCK2MAPTALDH1A1GAA | |
| SCHEMBL2558208 | 0.82 | ROCK1 (1.00) | ROCK1ROCK2 | |
| Hydrochloric Acid SCHEMBL2559843 | 0.81 | ROCK1 (0.98) | ROCK1ROCK2 | |
| SCHEMBL2553941 | 0.79 | ROCK1 (0.93) | ROCK1ROCK2 | |
| SCHEMBL91507 | 0.78 | ROCK2 (0.69) | ROCK1ROCK2MAPTALDH1A1MEN1 | |
| SCHEMBL91611 | 0.78 | FPR2 (0.55) | ROCK1ROCK2MAPTLMNAKMT2A | |
| SCHEMBL3815151 | 0.77 | ALDH1A1 (0.72) | ROCK2MAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ROCK1 2709/4885ROCK2 2794/4885MAPT 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.