Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054469 | 0.84 | ATM (0.56) | CTSLCTSBCTSSCTSKATM | |
| SCHEMBL9545565 | 0.84 | TRPM8 (0.57) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL14222479 | 0.82 | TRPM8 (0.56) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7430937 | 0.82 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7418088 | 0.82 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7245549 | 0.82 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7414480 | 0.82 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL6350990 | 0.82 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7198750 | 0.82 | ELANE (0.53) | CTRB1ALDH1A1ALOX15CTSLCTSB | |
| SCHEMBL7202814 | 0.82 | ELANE (0.53) | CTRB1ALDH1A1ALOX15CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239308-B1 | REARRANGEMENT IN PRESENCE OF A BASE A KETO-HEMIMERCAPTAL CARBOXYLATE | AJINOMOTO CO., INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0767168-B1 | Alpha-acyloxy-beta-aminothiolcarboxylic esters and method and intermediates for their production | AJINOMOTO KK (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6169200-B1 | ALPHA-ACYLOXY-THIOESTERS USEFUL ENZYME INHIBITORS, SUCH AS HIV PROTEASE AND RENIN | AJINOMOTO CO., INC. (JP) | 2001-01-02 | — | — | US | disclosed |
| US-5817859-A | CHEMICAL INTERMEDIATE FOR ENZYME INHIBITORS, ANTICARCER AGENTS | AJINOMOTO CO., INC. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5705671-A | REARRANGEMENTS TO FORM SULFOXY ESTER AMIDES FROM KETO HEMIMERCAPTAL CARBOXYLATE, REACTING N-PROTECTED ALPHA AMINO CARBOXYLATE WITH SULFOXIDE AND AMINO KETOSULFOXIDE | AJINOMOTO CO., INC. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0767168-A2 | Alpha-hydroxy-beta-aminothiolcarboxylic esters and method and intermediates for their production | Ajinomoto Co., Inc. (JP) | 1997-04-09 | — | — | EP | disclosed |