Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796585 | 0.88 | TRPM8 (0.55) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL2736202 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL4949767 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL2736218 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL7337287 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL5916913 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL9421829 | 0.87 | TRPM8 (0.64) | TRPM8CTRB1ALDH1A1ALOX15CTSD | |
| SCHEMBL9421798 | 0.85 | TRPM8 (0.52) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7763449 | 0.84 | TRPM8 (0.58) | TRPM8CTRB1ALDH1A1ALOX15TACR1 | |
| SCHEMBL7270655 | 0.82 | CTSD (0.62) | TRPM8CTSDCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023361-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED DIAMINODIOL | ABBOTT LABORATORIES (US) | 1993-11-25 | — | — | WO | disclosed |