Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18948435 | 0.83 | PLA2G4A (0.36) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL19334597 | 0.83 | PLA2G4A (0.36) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL21217035 | 0.83 | PLA2G4A (0.36) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL18430567 | 0.83 | PLA2G4A (0.36) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL29325457 | 0.83 | PLA2G4A (0.36) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL1670553 | 0.81 | CA2 (0.39) | PLA2G4AL3MBTL1CA2 | |
| SCHEMBL20098093 | 0.81 | PLA2G4A (0.35) | PLA2G4AL3MBTL1FBP1HSPA5CTSK | |
| SCHEMBL29865290 | 0.80 | NR1I2 (0.38) | PLA2G4AL3MBTL1FBP1 | |
| SCHEMBL7267691 | 0.79 | L3MBTL1 (0.38) | PLA2G4AL3MBTL1HSPA5CTSKCYP1A2 | |
| SCHEMBL9095414 | 0.79 | L3MBTL1 (0.38) | PLA2G4AL3MBTL1HSPA5CTSKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |