Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401278 | 0.86 | ALDH1A1 (0.42) | SLC9A1ALDH1A1LMNAMAPK1 | |
| SCHEMBL5190885 | 0.85 | SLC9A1 (0.59) | SLC9A1ALDH1A1LMNAMAPK1 | |
| SCHEMBL21623170 | 0.84 | CA12 (0.38) | SLC9A1ALDH1A1LMNAMAPK1TTR | |
| SCHEMBL2968143 | 0.81 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8574555 | 0.81 | CA12 (0.53) | ALDH1A1LMNA | |
| SCHEMBL8578749 | 0.81 | CA12 (0.54) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL8055935 | 0.79 | GABRP (0.39) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL1763798 | 0.79 | CA12 (0.51) | SLC9A1ALDH1A1LMNAMAPK1 | |
| SCHEMBL6674304 | 0.79 | CISD1 (0.50) | SLC9A1ALDH1A1LMNAMAPK1 | |
| SCHEMBL6922321 | 0.79 | SLC9A1 (0.49) | SLC9A1ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723963-B1 | 4-amino-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000066552-A1 | METHOD FOR PRODUCING A BENZOYLGUANIDINE DERIVATIVE | MERCK PATENT GMBH (DE) | 2000-11-09 | — | — | WO | disclosed |
| EP-0704431-B1 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |
| EP-0723963-A1 | 4-amino-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |