Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981062 | 0.76 | MAPK1 (0.54) | KDM4EHSD17B10NPSR1MAPTMAPK1 | |
| SCHEMBL9622169 | 0.74 | METAP2 (0.68) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL6233509 | 0.74 | METAP2 (1.00) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL11097221 | 0.74 | CSNK1A1 (0.61) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9622853 | 0.74 | METAP2 (0.68) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL20647667 | 0.72 | METAP2 (0.54) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL2607725 | 0.70 | METAP2 (0.68) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL229709 | 0.70 | KDM4E (0.68) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL17681622 | 0.70 | METAP1 (0.52) | METAP2METAP1KDM4EHSD17B10NPSR1 | |
| SCHEMBL17681607 | 0.69 | METAP1 (0.50) | METAP2METAP1KDM4EHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100550-A1 | METHOD FOR THE MANUFACTURE OF ANTIMICROBIAL ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006210-A1 | METHOD FOR THE MANUFACTURE OF ANTIMICROBIAL ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |