Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765517 | 0.89 | SLC9A1 (0.44) | — | |
| SCHEMBL7764123 | 0.88 | SLC9A1 (0.54) | — | |
| SCHEMBL7765627 | 0.87 | SLC9A1 (0.44) | — | |
| SCHEMBL7764091 | 0.86 | SLC9A1 (0.48) | — | |
| SCHEMBL7768698 | 0.85 | — | — | |
| SCHEMBL8632259 | 0.85 | YAP1 (0.49) | YAP1TEAD4TEAD2 | |
| SCHEMBL7768696 | 0.83 | PDE4B (0.44) | — | |
| SCHEMBL7766539 | 0.83 | PDE4B (0.42) | — | |
| SCHEMBL7766594 | 0.82 | SLC9A1 (0.44) | — | |
| SCHEMBL7764085 | 0.82 | SLC9A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723963-B1 | 4-amino-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |