Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.71 |
| ▸ | CTSS | P25774 | 1/20 | 0.71 |
| ▸ | CTSK | P43235 | 1/20 | 0.71 |
| ▸ | TACR1 | P25103 | 2/20 | 0.65 |
| ▸ | NMBR | P28336 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073498 | 1.00 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL17643540 | 0.93 | CTSL (0.76) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL9113871 | 0.91 | CTSL (0.73) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10805328 | 0.90 | CTSL (0.59) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8387597 | 0.90 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8104485 | 0.88 | CA5A (0.61) | CTSLCTSBCTSSCTSKNMBR | |
| SCHEMBL10802560 | 0.88 | CTSL (0.73) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL4070768 | 0.88 | CTSL (0.76) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11709662 | 0.87 | CA5A (0.60) | CTSLCTSBCTSSCTSKNMBR | |
| SCHEMBL7762796 | 0.86 | CTSL (0.74) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |