Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
| ▸ | NMBR | P28336 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349223 | 0.93 | CAPN1 (0.56) | CA5ACA2CTSKCTRB1NMBR | |
| SCHEMBL13073498 | 0.88 | CTSL (0.71) | CA5ACA2CTSKNMBRCTSS | |
| SCHEMBL7764124 | 0.88 | CTSL (0.71) | CA5ACA2CTSKNMBRCTSS | |
| SCHEMBL7348355 | 0.87 | FNTA (0.61) | CA5ACA2CA1CTSKCTRB1 | |
| SCHEMBL11709662 | 0.86 | CA5A (0.60) | CA5ACA2CA1CTSKNMBR | |
| SCHEMBL29941583 | 0.86 | CTRB1 (0.58) | CTSKCTRB1CTSSCTSLCTSB | |
| SCHEMBL7351353 | 0.84 | CTRB1 (0.62) | CTSKCTRB1CTSSCTSLCTSB | |
| SCHEMBL2416694 | 0.82 | CTRB1 (0.67) | CTSKCTRB1CTSSCTSLCTSB | |
| SCHEMBL9544107 | 0.82 | CTRB1 (0.67) | CTSKCTRB1CTSSCTSLCTSB | |
| SCHEMBL6568131 | 0.82 | CTRB1 (0.67) | CTSKCTRB1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000056283-A1 | INHIBITION OF MATRIX METALLOPROTEINASES WITH POLYMERS AND PHARMACEUTICAL APPLICATIONS THEREOF | THE B.F.GOODRICH COMPANY (US) | 2000-09-28 | — | — | WO | disclosed |