Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | BMP1 | P13497 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764176 | 1.00 | BCHE (0.39) | BCHERENCTSSCTSKMAPT | |
| SCHEMBL6943422 | 1.00 | BCHE (0.39) | BCHERENCTSSCTSKMAPT | |
| SCHEMBL6943418 | 1.00 | BCHE (0.39) | BCHERENCTSSCTSKMAPT | |
| SCHEMBL7928707 | 0.99 | BCHE (0.37) | BCHERENCTSSCTSKMAPT | |
| SCHEMBL7815506 | 0.99 | BCHE (0.37) | BCHERENCTSSCTSKMAPT | |
| SCHEMBL6986468 | 0.96 | BCHE (0.38) | BCHERENCTSSCTSKEPHX1 | |
| SCHEMBL6939989 | 0.83 | BCHE (0.39) | BCHERENCTSSCTSKEPHX1 | |
| SCHEMBL6987806 | 0.82 | BCHE (0.37) | BCHERENCTSSCTSKEPHX1 | |
| SCHEMBL6945400 | 0.80 | CTSK (0.33) | RENCTSKSMN1; SMN2KMT2A | |
| SCHEMBL6946023 | 0.80 | CTSK (0.33) | RENCTSKSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161331-C | Hydrazine derivative | - | 2004-08-11 | — | — | CN | disclosed |
| CN-1148346-C | Hydrazine derivative | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1309634-A | Hydrazine derivs. | HOFFMANN LA ROCHE (CH) | 2001-08-22 | — | — | CN | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |
| CN-1265096-A | Hydrazine derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-30 | — | — | CN | disclosed |