Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764302 | 0.89 | LMNA (0.40) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7772368 | 0.85 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL8724005 | 0.81 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL8724009 | 0.81 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7764296 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL8725193 | 0.79 | LMNA (0.38) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7764305 | 0.77 | LMNA (0.37) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7772369 | 0.75 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL10119042 | 0.70 | ALDH1A1 (0.41) | LMNAALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7768401 | 0.70 | MAOB (0.33) | SMN1; SMN2GAARAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |