Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724005 | 1.00 | LMNA (0.39) | LMNAALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8725193 | 0.91 | LMNA (0.38) | LMNAALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7764296 | 0.83 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7764293 | 0.81 | LMNA (0.42) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7764305 | 0.81 | LMNA (0.37) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7764302 | 0.79 | LMNA (0.40) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7768401 | 0.79 | MAOB (0.33) | MAPTSMN1; SMN2MAPK1TDP1L3MBTL1 | |
| SCHEMBL7772369 | 0.77 | LMNA (0.36) | LMNAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10119042 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7772368 | 0.76 | ALDH1A1 (0.37) | LMNAALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |