Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767158 | 0.69 | — | — | |
| SCHEMBL7629299 | 0.65 | APP (0.35) | TDP1LMNANAPRTALDH1A1CES2 | |
| SCHEMBL3190528 | 0.61 | ALDH1A1 (0.55) | LMNAP4HTMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL292238 | 0.61 | ALDH1A1 (0.37) | TDP1LMNAL3MBTL1NAPRTALDH1A1 | |
| SCHEMBL10038833 | 0.61 | ALDH1A1 (0.35) | TDP1LMNAL3MBTL1NAPRTALDH1A1 | |
| Quinoxaline SCHEMBL27830916 | 0.61 | ALDH1A1 (0.55) | LMNAP4HTMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL38901 | 0.60 | ALDH1A1 (0.40) | TDP1LMNAL3MBTL1ALDH1A1KMT2A | |
| Benzene SCHEMBL28223369 | 0.60 | ALDH1A1 (0.40) | TDP1LMNAL3MBTL1ALDH1A1KMT2A | |
| Benzene SCHEMBL27879268 | 0.60 | ALDH1A1 (0.40) | TDP1LMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1778033 | 0.60 | ALDH1A1 (0.40) | TDP1LMNAALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097161-A1 | TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002891-A1 | TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2000-01-20 | — | — | WO | disclosed |