SCHEMBL10038833

SCHEMBL10038833

O=[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
TSHR P16473 5/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
ALOX15 P16050 1/20 0.33
HTR6 P50406 1/20 0.33
CYP2A6 P11509 1/20 0.33
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 4/20 0.32
CA2 P00918 3/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8707469 0.73
SCHEMBL8668815 0.73
SCHEMBL27484043 0.73
SCHEMBL292238 0.71 ALDH1A1 (0.37) ALDH1A1TSHRCES2CES1DAO
SCHEMBL31729905 0.71 LMNA (0.33) ALDH1A1TSHRLMNACA2CA1
SCHEMBL17395188 0.71 CA4 (0.36) ALDH1A1CES2CES1LMNATDP1
Potassium Ion SCHEMBL11223545 0.71 ALDH1A1 (0.32) ALDH1A1CES2CES1LMNATDP1
SCHEMBL38901 0.69 ALDH1A1 (0.40) ALDH1A1TSHRALOX15CYP2A6LMNA
SCHEMBL1778033 0.69 ALDH1A1 (0.40) ALDH1A1TSHRCYP2A6LMNAMAPT
Benzene SCHEMBL28223369 0.69 ALDH1A1 (0.40) ALDH1A1TSHRALOX15CYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043950-A1 POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM 万华化学集团股份有限公司 2025-03-06 WO disclosed
CN-119333349-A Light-ultrasonic-geothermal coupling combined energy supply system and method 青海民族大学 2025-01-21 CN disclosed
CN-220754681-U Photovoltaic thermoelectric-based integrated power generation device 昆明理工大学 2024-04-09 CN disclosed
WO-2019191547-A1 NOVEL FULLY SYNTHETIC AND SEMISYNTHETIC PLEUROMUTILIN DERIVATIVES AS NEW ANTIBIOTICS AND THEIR PREPARATION YALE UNIVERSITY (US) 2019-10-03 WO disclosed
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2018-01-04 US disclosed
US-9680103-B2 Organic photoelectric conversion element composition, thin film and photovoltaic cell each containing the same, organic semiconductor polymer and compound each for use in these, and method of producing the polymer FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20170158700-A1 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES TAKEDA CAMBRIDGE LIMITED (GB) 2017-06-08 US disclosed
US-9556327-B2 Additive for a silicone encapsulant DOW CORNING CORPORATION (US) 2017-01-31 US disclosed
US-9550783-B2 Biaryl heterocyclic compounds and methods of making and using the same MELINTA THERAPEUTICS, INC. (US) 2017-01-24 US disclosed
US-9493498-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2016-11-15 US disclosed
US-20120219593-A1 INDOLYLMALEIMIDE DERIVATIVES PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS NOVARTIS AG 2012-08-30 US disclosed
US-8193236-B2 Indolylmaleimide derivatives processes for their production and pharmaceutical compositions NOVARTIS AG (CH) 2012-06-05 US disclosed
US-20120010200-A1 Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same RIB-X PHARMACEUTICALS, INC. 2012-01-12 US disclosed
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2011-12-08 US disclosed
US-RE43003-E1 Epothilone derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 2011-12-06 US disclosed
US-20110092458-A1 Use of (R)-Penciclovir Triphosphate for the Manufacture of a Medicament for the Treatment of Viral Diseases NOVARTIS PHARMACEUTICALS CORPORATION 2011-04-21 US disclosed
US-RE41911-E1 such as [1S-[1R*,3R*(E),7R*,10S*,11R*,12R*,16S*]]-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4-aza-17-oxabicyclo[14.1.0]heptadecane-5,9-dione, used as anticarcinogenic agents BRISTOL-MYERS SQUIBB COMPANY (US) 2010-11-02 US disclosed
US-20100234591-A1 BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME RIB-X PHARMACEUTICALS, INC. (US) 2010-09-16 US disclosed
US-7705026-B2 Biaryl heterocyclic compounds and methods of making and using the same RIB-X PHARMACEUTICALS, INC. (US) 2010-04-27 US disclosed
US-7368437-B1 Bicyclic heterocycles, processes for their preparation and their use as herbicides and pharmaceutical agents BAYER CROPSCIENCE AG (DE) 2008-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092458-A1 Use of (R)-Penciclovir Triphosphate for the Manufacture of a Medicament for the Treatment of Viral Diseases TYMP, PNP, HPRT1 ALDH1A1 1921/4885TSHR 3462/4885CES2 1639/4885
US-20100234591-A1 BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PCNA, AADAC, MIF ALDH1A1 2099/4885TSHR 3560/4885CES2 1756/4885
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 ALDH1A1 2313/4885TSHR 2930/4885CES2 1057/4885
US-20120010200-A1 Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same PCNA, AADAC, MIF ALDH1A1 2099/4885TSHR 3560/4885CES2 1756/4885
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 ALDH1A1 2313/4885TSHR 2930/4885CES2 1057/4885
US-20170158700-A1 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES NPY5R, XDH, NPY4R ALDH1A1 1979/4885TSHR 669/4885CES2 2254/4885
US-20120219593-A1 INDOLYLMALEIMIDE DERIVATIVES PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS RB1, INMT, IDH3A ALDH1A1 129/4885TSHR 1676/4885CES2 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.