Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449448 | 0.76 | MAOA (0.48) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL4768655 | 0.74 | PTGS2 (0.42) | MAOACES1BCHEALDH1A1MAP2K7 | |
| SCHEMBL10026452 | 0.73 | HRH4 (0.40) | BCHEALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL5311573 | 0.73 | MAOA (0.50) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL1818127 | 0.72 | MAOA (0.48) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL4000976 | 0.72 | MAOA (0.48) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL670717 | 0.72 | MAOA (0.48) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL7716195 | 0.71 | MAOA (0.44) | MAOACES1BCHEALDH1A1ACHE | |
| SCHEMBL11406516 | 0.71 | CCNB2 (0.45) | MAOACES1BCHEALDH1A1MAP2K7 | |
| SCHEMBL7264066 | 0.71 | MAOA (0.44) | MAOACES1BCHEALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |