Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 11/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761516 | 0.83 | FKBP1A (0.40) | DRD2SLC6A4FKBP1ARIPK1 | |
| SCHEMBL7429157 | 0.81 | FKBP1A (0.39) | FKBP1ARIPK1 | |
| SCHEMBL6570607 | 0.81 | FKBP1A (0.39) | FKBP1ARIPK1 | |
| SCHEMBL8485753 | 0.77 | PSEN1 (0.35) | FKBP1ARIPK1 | |
| SCHEMBL6049184 | 0.75 | RIPK1 (0.40) | FKBP1ARIPK1 | |
| SCHEMBL5700697 | 0.74 | FKBP1A (0.33) | FKBP1ARIPK1 | |
| SCHEMBL5282826 | 0.68 | FKBP1A (0.35) | FKBP1A | |
| SCHEMBL5282825 | 0.64 | FKBP1A (0.40) | FKBP1ARIPK1 | |
| SCHEMBL5700676 | 0.62 | FKBP1A (0.41) | FKBP1ARIPK1 | |
| SCHEMBL7411203 | 0.61 | FKBP1A (0.39) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104298-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-06 | — | — | EP | claimed |
| WO-2000009479-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| EP-1104298-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009479-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |