Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485753 | 0.85 | PSEN1 (0.35) | FKBP1ARIPK1 | |
| SCHEMBL7761516 | 0.79 | FKBP1A (0.40) | FKBP1ARIPK1 | |
| SCHEMBL6049184 | 0.78 | RIPK1 (0.40) | FKBP1ARIPK1 | |
| SCHEMBL7429157 | 0.74 | FKBP1A (0.39) | FKBP1ARIPK1 | |
| SCHEMBL7764589 | 0.74 | DRD2 (0.36) | FKBP1ARIPK1 | |
| SCHEMBL6049369 | 0.71 | TP53 (0.31) | — | |
| SCHEMBL6570607 | 0.70 | FKBP1A (0.39) | FKBP1ARIPK1 | |
| SCHEMBL4677187 | 0.67 | FKBP1A (0.38) | FKBP1A | |
| SCHEMBL7763916 | 0.65 | FKBP1A (0.35) | FKBP1A | |
| SCHEMBL5700694 | 0.65 | OPRM1 (0.36) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083873-B1 | HETEROCYCLIC THIOESTER AND KETONE HAIR GROWTH COMPOSITIONS AND USES | MGI GP INC (US) | 2006-08-09 | — | — | EP | claimed |
| EP-0934263-B8 | NON-IMMUNOSUPPRESSANT FKBP ROTAMASE INHIBITORS | MGI GP INC (US) | 2006-01-18 | — | — | EP | claimed |
| EP-0934263-A4 | HETEROCYCLIC THIOESTERS AND KETONES | GUILFORD PHARM INC (US) | 2002-11-06 | — | — | EP | claimed |
| JP-2001506231-A | — | — | 2001-05-15 | — | — | JP | claimed |
| EP-0934263-A1 | HETEROCYCLIC THIOESTERS AND KETONES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998013343-A1 | HETEROCYCLIC THIOESTERS AND KETONES | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |