Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764590 | 0.90 | MEN1 (0.58) | MEN1KMT2AALDH1A1CNR2CNR1 | |
| SCHEMBL7768178 | 0.79 | MAPT (0.57) | MEN1KMT2AALDH1A1CNR2CNR1 | |
| SCHEMBL7764603 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7768185 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7768176 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13932723 | 0.75 | MAPT (0.63) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7768515 | 0.74 | SGMS2 (0.52) | MEN1KMT2AALDH1A1CNR2CNR1 | |
| SCHEMBL7564957 | 0.74 | MEN1 (0.46) | MEN1KMT2ACNR2CNR1EPHX2 | |
| SCHEMBL14199506 | 0.73 | FAAH (0.63) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL13528229 | 0.73 | MAPT (0.66) | MEN1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929515-B1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CONSEILS DE RECH S SOC D (FR) | 2001-06-20 | — | — | EP | claimed |
| US-5998666-A | ANTIULCER, ANTISECRETORY AGENTS; ANTIEMITIC | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1999-12-07 | — | — | US | claimed |
| EP-0929515-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013337-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | claimed |
| EP-0929515-B1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CONSEILS DE RECH S SOC D (FR) | 2001-06-20 | — | — | EP | disclosed |
| US-6150417-A | ADMINISTERING TO WARM BLOODED ANIMALS COMPOUNDS SUCH AS N-TERT-BUTYL-5-((2-(2-METHOXYPHENOXY)ETHYL)AMINO)PENTANAMIDE FOR INDUCING ANTIEMETIC ACTIVITY; TREATING ANXIETY, DEPRESSION, AND SLEEP DISORDERS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| US-5998666-A | ANTIULCER, ANTISECRETORY AGENTS; ANTIEMITIC | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1999-12-07 | — | — | US | disclosed |
| EP-0929515-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013337-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |