Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157363 | 0.96 | HMGCR (0.46) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL10015433 | 0.84 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL20182218 | 0.83 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL9879684 | 0.82 | HMGCR (0.53) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL17831295 | 0.81 | HTR2A (0.46) | RXRARXRBRXRG | |
| SCHEMBL17831296 | 0.81 | HTR2A (0.46) | RXRARXRBRXRG | |
| SCHEMBL1652967 | 0.79 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL7764667 | 0.78 | HMGCR (0.50) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL8679307 | 0.78 | TSHR (0.58) | TP53TSHR | |
| SCHEMBL18253225 | 0.78 | TSHR (0.58) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675153-B1 | Process for the preparation of star-shaped polymers | SHELL INT RESEARCH (NL) | 2001-06-13 | — | — | EP | disclosed |
| EP-1099717-A2 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| US-5458796-A | Synthesis of polyisobutylene star-branched polymers via living carbocationic polymerization | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0675153-A1 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-10-04 | — | — | EP | disclosed |