Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764606 | 0.84 | HMGCR (0.50) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL20182218 | 0.81 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL6157363 | 0.80 | HMGCR (0.46) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL9879684 | 0.79 | HMGCR (0.53) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL962215 | 0.78 | GABRA1 (0.52) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL6058033 | 0.78 | KDM6B (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL16819804 | 0.78 | IDO1 (0.38) | HMGCRGABRA1GABRB2CYP2C19TSHR | |
| SCHEMBL1652967 | 0.77 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| Methane SCHEMBL27239080 | 0.77 | KDM6B (0.46) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL7764667 | 0.76 | HMGCR (0.50) | HMGCRGABRA1GABRB2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120025183-A1 | NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120025183-A1 | NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS | ACE, ACE2, AGTR1 | HMGCR 3466/4885GABRA1 1846/4885GABRB2 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.