Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45261 | 0.96 | HMGCR (0.46) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL3683050 | 0.84 | HMGCR (0.39) | HMGCRTP53TSHR | |
| SCHEMBL9879684 | 0.82 | HMGCR (0.53) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL2332071 | 0.81 | HTR2A (0.46) | RXRARXRBRXRGTP53TSHR | |
| SCHEMBL4445053 | 0.80 | HTR2A (0.50) | TP53TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL7764606 | 0.78 | HMGCR (0.50) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL45291 | 0.78 | PNMT (0.33) | TP53POLBHTR2AHTR2BCYP2C19 | |
| SCHEMBL25774449 | 0.77 | HMGCR (0.49) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL10015433 | 0.76 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB | |
| SCHEMBL1652967 | 0.75 | HMGCR (0.47) | HMGCRGABRA1GABRB2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5458796-A | Synthesis of polyisobutylene star-branched polymers via living carbocationic polymerization | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | claimed |
| EP-0675153-B1 | Process for the preparation of star-shaped polymers | SHELL INT RESEARCH (NL) | 2001-06-13 | — | — | EP | disclosed |
| EP-1099717-A2 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| US-5458796-A | Synthesis of polyisobutylene star-branched polymers via living carbocationic polymerization | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0675153-A1 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-10-04 | — | — | EP | disclosed |