Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CDA | P32320 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685622 | 1.00 | MAPT (0.51) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL16781797 | 1.00 | MAPT (0.51) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL31685600 | 0.86 | TK2 (0.44) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL635155 | 0.85 | MAPT (0.47) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL5903970 | 0.85 | PYGM (0.49) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL7640658 | 0.85 | MAPT (0.47) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL5903974 | 0.85 | PYGM (0.49) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2908553 | 0.85 | MAPT (0.50) | MAPTCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL12718534 | 0.85 | TYMP (0.53) | MAPTCDATYMPPYGMSLC5A2 | |
| SCHEMBL12718548 | 0.85 | TYMP (0.53) | MAPTCDATYMPPYGMSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098887-A1 | SUBSTITUTED 6-BENZYL-4-OXOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novirio Pharmaceuticals Limited (KY) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003998-A1 | SUBSTITUTED 6-BENZYL-4-OXOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVIRIO PHARMACEUTICALS LIMITED (KY) | 2000-01-27 | — | — | WO | disclosed |