SCHEMBL16781797

SCHEMBL16781797

Cc1cn([C@H]2O[C@@H](CO)C(O)C2O)c(=O)n(C)c1=O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.51
▸ CDA P32320 1/20 0.51
▸ SLC28A1 O00337 1/20 0.50
▸ SLC28A2 O43868 1/20 0.50
▸ SLC29A1 Q99808 1/20 0.50
▸ SLC28A3 Q9HAS3 1/20 0.50
▸ TYMP P19971 1/20 0.48
▸ PYGM P11217 3/20 0.47
▸ SLC5A2 P31639 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685622 1.00 MAPT (0.51) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL7764746 1.00 MAPT (0.51) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL31685600 0.86 TK2 (0.44) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL635155 0.85 MAPT (0.47) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL5903970 0.85 PYGM (0.49) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL7640658 0.85 MAPT (0.47) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL5903974 0.85 PYGM (0.49) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL2908553 0.85 MAPT (0.50) MAPTCDASLC28A1SLC28A2SLC29A1
SCHEMBL12718534 0.85 TYMP (0.53) MAPTCDATYMPPYGMSLC5A2
SCHEMBL12718548 0.85 TYMP (0.53) MAPTCDATYMPPYGMSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024118866-A1 GPC3-SPECIFIC ANTIBODIES, BINDING DOMAINS, AND RELATED PROTEINS AND USES THEREOF MODERNATX, INC. (US) 2024-06-06 — — WO disclosed
WO-2024112568-A1 ANTISENSE OLIGOMER (ASO) AS AN INHIBITOR OF LIVER FIBROSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-30 — — WO disclosed
US-20240165267-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2024-05-23 — — US disclosed
WO-2024097639-A1 HSA-BINDING ANTIBODIES AND BINDING PROTEINS AND USES THEREOF MODERNATX, INC. (US) 2024-05-10 — — WO disclosed
WO-2024044741-A2 EFFICIENT METHOD FOR MAKING HIGHLY PURIFIED 5'-CAPPED OLIGONUCLEOTIDES TRILINK BIOTECHNOLOGIES, LLC (US) 2024-02-29 — — WO disclosed
WO-2024031087-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-02-08 — — WO disclosed
WO-2023235749-A2 RNA ADJUVANTS, METHODS AND USES THEREOF FLAG BIO, INC. (US) 2023-12-07 — — WO disclosed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 — — WO disclosed
WO-2023014974-A1 DOUBLE STRANDED MRNA VACCINES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2023-02-09 — — WO disclosed
US-20220192997-A1 VIRION-LIKE DELIVERY PARTICLES FOR SELF-REPLICATING RNA MOLECULES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-06-23 — — US disclosed
US-20160354493-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX, INC. 2016-12-08 — — US disclosed
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2016-12-08 — — US disclosed
US-20160348099-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2016-12-01 — — US disclosed
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2016-10-20 — — US disclosed
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2016-09-15 — — US disclosed
EP-3053585-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2016-08-10 — — EP disclosed
EP-2918275-B1 Alternative nucleic acid molecules and uses thereof MODERNA THERAPEUTICS INC (US) 2016-05-18 — — EP disclosed
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX, INC. 2015-10-29 — — US disclosed
EP-2918275-A1 Alternative nucleic acid molecules and uses thereof Roy, Atanu (US) 2015-09-16 — — EP disclosed
US-20150167017-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2015-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF POLRMT, POLN, NSUN3 MAPT 3290/4885CDA 200/4885SLC28A1 302/4885
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885
US-20160348099-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885
US-20240165267-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885
US-20160354493-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 MAPT 3517/4885CDA 46/4885SLC28A1 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback