Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CDA | P32320 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5903970 | 1.00 | PYGM (0.49) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL17504390 | 0.87 | TK2 (0.42) | PYGMSLC5A2MAPTCDATYMP | |
| SCHEMBL16781797 | 0.85 | MAPT (0.51) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL31685622 | 0.85 | MAPT (0.51) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL7764746 | 0.85 | MAPT (0.51) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL635155 | 0.84 | MAPT (0.47) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL7640658 | 0.84 | MAPT (0.47) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL17504389 | 0.83 | CDK1 (0.38) | PYGMSLC5A2MAPTCDASLC28A1 | |
| SCHEMBL11665141 | 0.83 | MAPT (0.48) | PYGMMAPTCDASLC28A1SLC28A2 | |
| SCHEMBL3414315 | 0.82 | ALDH1A1 (0.45) | PYGMMAPTCDASLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105915-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | MARKER GENE TECHNOLOGIES, INC. | 2006-05-18 | — | — | US | disclosed |
| US-6656917-B1 | Enzyme encoded by vector recognizes and binds to the inactive conjugate, and releases the bioactive compound from conjugation in an amount effective to enhance growth | MARKER GENE TECHNOLOGIES, INC. | 2003-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105915-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | GUSB, PREP, PEPD | PYGM 380/4885SLC5A2 4145/4885MAPT 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.