SCHEMBL7764771

SCHEMBL7764771

CN(C)c1ccc2c(c1)C(=O)OC2(c1ccn(C)c1)c1ccccc1N(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TDP1 Q9NUW8 4/20 0.56
CYP3A4 P08684 3/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
HIF1A Q16665 1/20 0.56
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
LMNA P02545 5/20 0.35
NPSR1 Q6W5P4 3/20 0.35
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
MAPT P10636 5/20 0.34
POLB P06746 3/20 0.34
FTO Q9C0B1 2/20 0.34
HTT P42858 2/20 0.34
GPR55 Q9Y2T6 2/20 0.34
ALOX12 P18054 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27648758 0.88 TDP1 (0.67) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL1446856 0.86 ALDH1A1 (0.76) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL29791059 0.86 ALDH1A1 (0.76) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL2905368 0.85 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL18143537 0.84 ALDH1A1 (0.62) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL4787639 0.81 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL15346931 0.79 ALDH1A1 (0.63) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL10689289 0.78 ALDH1A1 (0.82) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL7764773 0.77 ALDH1A1 (0.43) ALDH1A1TDP1CYP3A4HPGDHSD17B10
SCHEMBL10690656 0.76 TDP1 (0.56) ALDH1A1TDP1CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405220-A1 HOT MELT WETNESS INDICATOR COMPOSITION THAT INCLUDES A LEUCO DYE, AND ARTICLES INCLUDING THE SAME H.B. Fuller Company (US) 2018-11-28 EP disclosed
US-20160303275-A1 LEUCO DYES WITH HOT MELT BINDING MATRIX THE PROCTER & GAMBLE COMPANY 2016-10-20 US disclosed
WO-2016161329-A1 HOT MELT WETNESS INDICATOR COMPOSITION THAT INCLUDES A LEUCO DYE, AND ARTICLES INCLUDING THE SAME H.B. FULLER COMPANY (US) 2016-10-06 WO disclosed
EP-2890413-A2 A COLOR-CHANGING COMPOSITION AND MATERIAL Kimberly-Clark Worldwide, Inc. (US) 2015-07-08 EP disclosed
EP-2819713-A2 WATER-BASED WETNESS-INDICATING COMPOSITION AND SENSOR Kimberly-Clark Worldwide, Inc. (US) 2015-01-07 EP disclosed
EP-2782537-A1 NON-TACKY WETNESS INDICATOR COMPOSITION FOR APPLICATION ON A POLYMERIC SUBSTRATE Kimberly-Clark Worldwide, Inc. (US) 2014-10-01 EP disclosed
EP-2756295-A2 WETNESS INDICATOR HAVING VARIED HUES Kimberly-Clark Worldwide, Inc. (US) 2014-07-23 EP disclosed
WO-2014033587-A2 A COLOR-CHANGING COMPOSITION AND MATERIAL KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-03-06 WO disclosed
EP-2658498-A2 ABSORBENT ARTICLE INCLUDING TWO DIMENSIONAL CODE MADE FROM AN ACTIVE GRAPHIC Kimberly-Clark Worldwide, Inc. (US) 2013-11-06 EP disclosed
EP-2654652-A2 ABSORBENT ARTICLES WITH MULTIPLE ACTIVE GRAPHICS Kimberly-Clark Worldwide, Inc. (US) 2013-10-30 EP disclosed
WO-2000007071-A1 COLOUR CHANGING COMPOSITION AND COLOURING POLYMERIC ARTICLES MADE THEREFROM VANTICO LIMITED (GB) 2000-02-10 WO disclosed
EP-0854783-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1998-07-29 EP disclosed
WO-1997009168-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1997-03-13 WO disclosed
EP-0382523-A2 Heat-sensitive record material NEW OJI PAPER CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0373251-A1 Additive for heat-sensitive recording material, the recording material, and method for production of the recording material SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-06-20 EP disclosed
EP-0358193-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-14 EP disclosed
EP-0345755-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-12-13 EP disclosed
EP-0337426-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-10-18 EP disclosed
EP-0326964-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0308978-A2 Multi-color heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-03-29 EP disclosed