Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533499 | 0.86 | TAAR1 (0.39) | TAAR1 | |
| SCHEMBL10719547 | 0.85 | LIPG (0.34) | TAAR1SLC6A4MGLLLIPG | |
| SCHEMBL27854231 | 0.82 | TAAR1 (0.41) | TAAR1SLC6A4 | |
| SCHEMBL5869932 | 0.80 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL8467567 | 0.77 | POLB (0.38) | TAAR1SLC6A2SLC6A4LIPG | |
| SCHEMBL11576484 | 0.77 | ALDH1A1 (0.34) | TAAR1LIPG | |
| SCHEMBL7453023 | 0.77 | TDP1 (0.36) | TAAR1LIPG | |
| SCHEMBL392416 | 0.77 | LIPG (0.47) | LIPG | |
| SCHEMBL3403865 | 0.77 | LIPG (0.34) | MGLLLIPG | |
| SCHEMBL577388 | 0.76 | TAAR1 (0.56) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085221-A2 | ASSESSING LEVELS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE IN VIVO | DUKE UNIVERSITY (US) | 2001-11-15 | — | — | WO | claimed |
| US-20120270812-A1 | COMPOSITIONS, METHODS, AND KITS FOR DETERMINING AN ALKYL TRANSFERASE | DUKE UNIVERSITY (US) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270812-A1 | COMPOSITIONS, METHODS, AND KITS FOR DETERMINING AN ALKYL TRANSFERASE | UNG, DNTT, OGG1 | TAAR1 581/4885SLC6A2 1243/4885SLC6A4 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.