Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398802 | 0.70 | TNKS (0.34) | TNKSTNKS2SMN1; SMN2 | |
| SCHEMBL7765004 | 0.70 | KIF11 (0.33) | — | |
| SCHEMBL12308063 | 0.62 | ESR1 (0.44) | — | |
| SCHEMBL34009 | 0.61 | KIF11 (0.48) | — | |
| SCHEMBL18981157 | 0.61 | — | — | |
| SCHEMBL8396111 | 0.61 | MAOB (0.53) | — | |
| SCHEMBL30528494 | 0.61 | TNKS2 (0.41) | TNKSTNKS2 | |
| Hydrogen Sulfide SCHEMBL28197187 | 0.59 | KIF11 (0.46) | — | |
| SCHEMBL28485167 | 0.59 | MAPT (0.45) | — | |
| SCHEMBL5698850 | 0.59 | KIF11 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |