Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767445 | 0.73 | CRBN (0.42) | — | |
| SCHEMBL7313446 | 0.72 | HTT (0.39) | KIF11 | |
| SCHEMBL7307081 | 0.72 | HTT (0.39) | KIF11 | |
| SCHEMBL7764976 | 0.70 | TNKS (0.32) | — | |
| SCHEMBL7310163 | 0.68 | HTT (0.54) | — | |
| SCHEMBL7315945 | 0.68 | HTT (0.54) | — | |
| SCHEMBL18742139 | 0.66 | KIF11 (0.37) | KIF11 | |
| SCHEMBL7767450 | 0.64 | CRBN (0.41) | — | |
| SCHEMBL17859347 | 0.63 | KIF11 (0.46) | KIF11 | |
| SCHEMBL7767482 | 0.63 | CRBN (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |