SCHEMBL776510

SCHEMBL776510

C=CCOP(C)(=O)OCC=C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
PKM P14618 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3185083 0.87
SCHEMBL29779753 0.87 LPAR3 (0.41) LPAR2LPAR3PKMALDH1A1
SCHEMBL11490361 0.87 MEN1 (0.33) LPAR2LPAR3PKMALDH1A1
SCHEMBL4812026 0.83
SCHEMBL11496486 0.83 CYP3A4 (0.48) LPAR2LPAR3ALDH1A1
SCHEMBL11356044 0.83 ACHE (0.46)
SCHEMBL6380953 0.80
SCHEMBL6381791 0.79
SCHEMBL4272824 0.79
SCHEMBL9625572 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820363-A Method for preparing L-glufosinate-ammonium by using phosphine reagent 摩珈(上海)生物科技有限公司 2024-04-05 CN claimed
US-11820749-B2 Centrally active and orally bioavailable uncharged bisoxime antidotes for organophosphate poisoning and methods for making and using them THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-11-21 US claimed
CN-113169395-B Electrolyte for lithium air battery and lithium air battery using same 国立研究开发法人物质·材料研究机构 2023-09-29 CN claimed
US-20220227724-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE UNCHARGED BISOXIME ANTIDOTES FOR ORGANOPHOSPHATE POISONING AND METHODS FOR MAKING AND USING THEM OAK RIDGE NATIONAL LABORATORY 2022-07-21 US claimed
US-20220045389-A1 ELECTROLYTE FOR LITHIUM AIR BATTERIES, AND LITHIUM AIR BATTERY USING THE SAME NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2022-02-10 US claimed
CN-113169395-A Electrolyte for lithium-air battery and lithium-air battery using same 国立研究开发法人物质·材料研究机构 2021-07-23 CN claimed
US-10913726-B2 Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-09 US claimed
WO-2020237079-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE UNCHARGED BISOXIME ANTIDOTES FOR ORGANOPHOSPHATE POISONING AND METHODS FOR MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-11-26 WO claimed
WO-2020142503-A1 THERAPEUTIC COMBINATIONS AS ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-07-09 WO claimed
US-20190119237-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-04-25 US claimed
US-10060887-B2 Field sampling kit and methods for collecting and detecting alkyl methylphosphonic acids THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2018-08-28 US claimed
EP-2956451-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM The Regents of the University of California (US) 2015-12-23 EP claimed
US-20150361060-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-12-17 US claimed
WO-2014127315-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-21 WO claimed
US-20140113380-A1 FIELD SAMPLING KIT AND METHODS FOR COLLECTING AND DETECTING ALKYL METHYLPHOSPHONIC ACIDS U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2014-04-24 US claimed
WO-2012138384-A1 FIELD SAMPLING KIT AND METHODS FOR COLLECTING AND DETECTING ALKYL METHYLPHOSPHONIC ACIDS U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2012-10-11 WO claimed
US-4108746-A IRRADIATING TO INDUCE OXIDATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1978-08-22 US claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-3972960-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-08-03 US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220227724-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE UNCHARGED BISOXIME ANTIDOTES FOR ORGANOPHOSPHATE POISONING AND METHODS FOR MAKING AND USING THEM BCHE, ACHE, FHIT LPAR2 3176/4885LPAR3 2810/4885PKM 1214/4885
US-20150361060-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM ACHE, BCHE, IDE LPAR2 2940/4885LPAR3 2357/4885PKM 2542/4885
US-11820749-B2 Centrally active and orally bioavailable uncharged bisoxime antidotes for organophosphate poisoning and methods for making and using them BCHE, ACHE, FHIT LPAR2 3176/4885LPAR3 2810/4885PKM 1214/4885
US-20190119237-A1 CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM ACHE, BCHE, IDE LPAR2 2940/4885LPAR3 2357/4885PKM 2542/4885
US-10913726-B2 Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them ACHE, BCHE, IDE LPAR2 2940/4885LPAR3 2357/4885PKM 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.