Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | BCR | P11274 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529161 | 0.86 | ABL1 (0.55) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL4375331 | 0.84 | PPARA (0.53) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL11994140 | 0.81 | PPARA (0.51) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL1520607 | 0.80 | ABL1 (0.56) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL13675365 | 0.80 | ABL1 (0.56) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL5538023 | 0.79 | DPP4 (0.56) | FFAR1FFAR4HDAC2HTR7 | |
| SCHEMBL2096587 | 0.79 | ABCB1 (0.44) | ABCB1HTR7NPC1TSHRRAB9A | |
| SCHEMBL2098044 | 0.79 | FFAR4 (0.52) | FFAR1FFAR4MAPTRAB9APPARA | |
| SCHEMBL10821571 | 0.79 | ABL1 (0.55) | ABL1ABCB1BCRFFAR1FFAR4 | |
| SCHEMBL3756401 | 0.79 | DPP4 (0.62) | ABL1ABCB1BCRFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104298-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009479-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |