Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9143002 | 0.93 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL7759522 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL30059020 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL7548043 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL24124204 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL4694745 | 0.85 | MAPT (0.47) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL8460319 | 0.84 | MEN1 (0.52) | ALDH1A1KDM4EMAPTHTTMEN1 | |
| SCHEMBL8102062 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHTTTDP1 | |
| SCHEMBL23705035 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTSRD5A2SRD5A1 | |
| SCHEMBL10693463 | 0.81 | ATM (0.42) | ALDH1A1KDM4EMAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DOEHNER JR ROBERT FRANCIS (US) | 2001-08-16 | — | — | US | claimed |
| EP-0915092-B1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | BASF AG (DE) | 2001-06-13 | — | — | EP | claimed |
| US-6008402-A | REACTING CYCLOHEXADIENECARBOXYLATE-4-ONE COMPOUND WITH A BETA MERCAPTOPROPIONIC ACID TO GIVE THIOENOL, CYCLODEHYDRATING THE THIOENOL | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | claimed |
| EP-0915092-A1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | American Cyanamid Company (US) | 1999-05-12 | — | — | EP | claimed |
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |
| CN-1326838-C | Benzo[d]azepine derivatives for the treatment of neurological disorders | GLAXO GROUP LTD (GB) | 2007-07-18 | — | — | CN | disclosed |
| CN-1496987-A | Pyrazole derivatives | ������������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1142930-C | Pyrazole derivatives | ������������ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| CN-1077106-C | Pyrazole derivatives | IDEMITSU KOSAN CO (JP) | 2002-01-02 | — | — | CN | disclosed |
| CN-1312248-A | Pyrazole derivatives | IDEMITSU KOSAN CO (JP) | 2001-09-12 | — | — | CN | disclosed |
| JP-2001163881-A | METHOD FOR PRODUCING THIOCHROMAN-6-CARBOXYLIC ACID DERIVATIVE OR DIHYDROBENZO[b]THIOPHENE-5-CARBOXYLIC ACID DERIVATIVE | IDEMITSU KOSAN CO LTD | 2001-06-19 | — | — | JP | disclosed |
| JP-2001163880-A | METHOD FOR PRODUCING THIOCHROMAN-6-CARBOXYLIC ACID DERIVATIVE OR DIHYDROBENZO[b]THIOPHENE-5-CARBOXYLIC ACID DERIVATIVE | IDEMITSU KOSAN CO LTD | 2001-06-19 | — | — | JP | disclosed |
| WO-2001040176-A1 | SULFIDE COMPOUND AND PROCESSES FOR PRODUCING THIOCHROMAN DERIVATIVE AND DIHYDROBENZ[B]THIOPHENE DERIVATIVE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |
| CN-1181080-A | Pyrazole derivatives | IDEMITSU KOSAN CO (JP) | 1998-05-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | ALDH1A1 2654/4885KDM4E 204/4885MAPT 4492/4885 |
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DDT, CYP4X1, CYP2B6 | ALDH1A1 119/4885KDM4E 1320/4885MAPT 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.