Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 6/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765521 | 0.89 | DRD4 (0.67) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7766439 | 0.81 | HTR1A (0.79) | KMT2AKDM4EALDH1A1HTR1ADRD4 | |
| SCHEMBL7765531 | 0.81 | DRD4 (0.64) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8403761 | 0.80 | HTR1A (0.77) | KMT2AKDM4EALDH1A1HTR1ADRD4 | |
| SCHEMBL8621651 | 0.79 | HTR1A (0.62) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL7762726 | 0.78 | MEN1 (0.62) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7765547 | 0.77 | USP2 (0.56) | MEN1KMT2AALDH1A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL8403646 | 0.77 | MEN1 (0.61) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10393710 | 0.75 | HTR1A (0.67) | MEN1KMT2AALDH1A1HTR1ADRD2 | |
| SCHEMBL25370948 | 0.75 | KDM4E (0.80) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | claimed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | claimed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | claimed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | claimed |
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | disclosed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | disclosed |
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | disclosed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |