Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765531 | 0.85 | DRD4 (0.64) | USP2MEN1KMT2AALDH1A1HTR1A | |
| SCHEMBL7765521 | 0.83 | DRD4 (0.67) | USP2MEN1KMT2AALDH1A1HTR1A | |
| SCHEMBL7765493 | 0.79 | HTR1A (0.60) | HTR1AMAPT | |
| SCHEMBL7765509 | 0.77 | MEN1 (0.64) | MEN1KMT2AALDH1A1HTR1ASLC6A2 | |
| SCHEMBL10982732 | 0.75 | HTR1A (0.66) | ALDH1A1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7762726 | 0.75 | MEN1 (0.62) | USP2MEN1KMT2AALDH1A1HTR1A | |
| SCHEMBL3372996 | 0.75 | PKM (0.63) | MEN1KMT2AALDH1A1TSHRTP53 | |
| Hydrochloric Acid SCHEMBL8403646 | 0.74 | MEN1 (0.61) | USP2MEN1KMT2AALDH1A1HTR1A | |
| SCHEMBL10392906 | 0.74 | HTR1A (0.62) | ALDH1A1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8407634 | 0.73 | HTR1A (0.52) | HTR1ASLC6A4DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | claimed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | claimed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | claimed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | claimed |
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | disclosed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | disclosed |
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | disclosed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |