Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7768534 | 0.75 | EED (0.42) | FFAR1L3MBTL1MEN1KMT2AALDH1A1 | |
| Cadaverine Tartrate SCHEMBL7765577 | 0.67 | CHRM4 (0.42) | FFAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL27989829 | 0.64 | MEN1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| Cadaverine Tartrate SCHEMBL8034056 | 0.63 | HSD11B1 (0.48) | ALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL27318039 | 0.63 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7764713 | 0.62 | EED (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL26128078 | 0.62 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30601824 | 0.62 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7511969 | 0.62 | TAAR1 (0.58) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1368547 | 0.62 | TAAR1 (0.58) | MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842153-B1 | METHOD OF PREPARING NORBENZOMORPHANE AS AN INTERMEDIATE IN THE PREPARATION OF PHARMACEUTICALLY USEFUL BENZOMORPHANE DERIVATIVES, IN PARTICULAR (-)-(1R,5S,2\"R)-3'-HYDROXY-2-(2-METHOXYPROPYL)-5,9,9-TRIMETHYL-6,7-BENZOMORPHANE | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-05-30 | — | — | EP | claimed |
| US-5945535-A | Method of preparing norbenzomorphanes | BOEHRINGER INGELHEIM KG (DE) | 1999-08-31 | — | — | US | claimed |
| US-6140502-A | Heat-based process for the re-racemisation of a (-)-2-phenylmethyl-3,3-dimethyl-piperidin-4-on derivative | BOEHRINGER INGELHEIM KG (DE) | 2000-10-31 | — | — | US | disclosed |
| US-6136980-A | Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2\"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane | BOEHRINGER INGELHEIM KG (DE) | 2000-10-24 | — | — | US | disclosed |
| US-6054604-A | Method of preparing norbenzomorphane as an intermediate | BOEHRINGER INGELHEIM KG (DE) | 2000-04-25 | — | — | US | disclosed |
| US-5945535-A | Method of preparing norbenzomorphanes | BOEHRINGER INGELHEIM KG (DE) | 1999-08-31 | — | — | US | disclosed |