Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019069 | 0.88 | LMNA (0.66) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL10576031 | 0.85 | SYK (0.47) | LMNASMN1; SMN2HTTSYKKMT2A | |
| SCHEMBL11278594 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL30400523 | 0.85 | HTT (0.54) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL334682 | 0.84 | LMNA (0.56) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL1568538 | 0.84 | LMNA (0.56) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL1569295 | 0.84 | LMNA (0.56) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL31207736 | 0.82 | LMNA (0.58) | LMNASMN1; SMN2HTTSYKSLC1A3 | |
| SCHEMBL19000309 | 0.82 | CTRB1 (0.53) | LMNASMN1; SMN2CTRB1CTSLCTSS | |
| SCHEMBL5019087 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTSYKSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636363-B1 | Drug delivery system | TERUMO CORP (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0636363-A2 | Drug delivery system | TERUMO KABUSHIKI KAISHA (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0012278-B1 | PREPARATION OF N-SUBSTITUTED DERIVATIVES OF 1-DEOXY-NOJIRIMYCINE | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4266025-A | Production of N-substituted derivatives of 1-desoxy-nojirimycin | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| EP-0012278-A2 | Preparation of N-substituted derivatives of 1-deoxy-nojirimycine | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |