SCHEMBL7765645

SCHEMBL7765645

[c]1nccnc1Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
CALM1 P0DP23 1/20 0.42
ALDH1A1 P00352 3/20 0.36
CCNB2 O95067 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
CCNB3 Q8WWL7 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 2/20 0.35
CYP1A2 P05177 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489367 0.72 CALM1 (0.42) TAAR1CALM1ALDH1A1NPC1RAB9A
SCHEMBL818602 0.69 CALM1 (0.44) TAAR1CALM1ALDH1A1LMNACYP1A2
SCHEMBL8781507 0.69 CALM1 (0.55) TAAR1CALM1ALDH1A1CCNB2CDK1
SCHEMBL559143 0.68 MTOR (0.39) TAAR1ALDH1A1CCNB2CDK1CCNB1
SCHEMBL6906772 0.68 HSD17B10 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL4933630 0.67
SCHEMBL5408241 0.67
SCHEMBL4932594 0.67
SCHEMBL414019 0.67
SCHEMBL2329762 0.65 TAAR1 (0.42) TAAR1CALM1ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092236-A1 4-ALKYL HALIDE TRIAZINE COMPOUNDS USED AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-12-06 WO disclosed
WO-2001090085-A2 6-METHYL-4-TRIHALOMETHYLTRIAZINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-11-29 WO disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed