Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626796 | 0.74 | POLB (0.44) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL9479768 | 0.73 | HSD17B10 (0.48) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL11201496 | 0.71 | — | — | |
| SCHEMBL1029180 | 0.69 | HSD17B10 (1.00) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL7765645 | 0.68 | TAAR1 (0.44) | HSD17B10RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL400161 | 0.66 | POLB (0.70) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL2123171 | 0.66 | HSD17B10 (0.53) | HSD17B10RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL229404 | 0.66 | HDAC1 (0.53) | HSD17B10RAB9ANPC1ALDH1A1ABL1 | |
| SCHEMBL7589855 | 0.65 | LMNA (0.53) | HSD17B10HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5155818 | 0.64 | HDAC1 (0.52) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040022880-A1 | Extracts of mixed arctium lappa L., carrot and whole radish for treating hypertension, constipation and detoxification | SHI YUAN (US) | 2004-02-05 | — | — | US | disclosed |
| US-6428822-B1 | HOLISTIC TREATMENT TO HEAL ENTIRE BODY; DIETARY SUPPLEMENT TO BOOST IMMUNE SYSTEM; SIDE EFFECT REDUCTION | CHENGZHI LIFE SCIENCE COMPANY, LTD. (CN) | 2002-08-06 | — | — | US | disclosed |
| US-4559340-A | DIURETICS; GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| US-4559340-A | DIURETICS; GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |