SCHEMBL7765654

SCHEMBL7765654

CCCCc1ccc([Si](O[SiH2]c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([SiH2]O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.42
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
HTR2A P28223 1/20 0.36
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
RARB P10826 1/20 0.36
KCNH2 Q12809 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35
PSMB5 P28074 1/20 0.35
DHODH Q02127 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17196191 0.74 HSD11B1 (0.51) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
SCHEMBL18759723 0.73 ESR1 (0.31)
SCHEMBL10319574 0.73 HSD11B1 (0.50) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
SCHEMBL10320192 0.73 HSD11B1 (0.50) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
SCHEMBL9617737 0.73 HSD11B1 (0.50) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
SCHEMBL27871067 0.72 HSD11B1 (0.53) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
SCHEMBL10319114 0.71 HSD11B1 (0.49) HSD11B1ALDH1A1HPGDHSD17B10TRPV1
Butadiene SCHEMBL667352 0.71
Butylbenzyl SCHEMBL27439483 0.69 SIGMAR1 (0.55) HSD11B1ALDH1A1HPGDHSD17B10KCNH2
SCHEMBL6131261 0.69 ALDH1A1 (0.57) HSD11B1ALDH1A1HPGDHSD17B10TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1097161-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-09 EP disclosed
WO-2000002891-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2000-01-20 WO disclosed