SCHEMBL7765659

SCHEMBL7765659

N#Cc1cc(O)c(C#N)cc1O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.43
ESR2 Q92731 7/20 0.38
ESR1 P03372 6/20 0.38
XDH P47989 1/20 0.37
TTR P02766 2/20 0.36
ALB P02768 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
UPP1 Q16831 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
AR P10275 4/20 0.34
GPR35 Q9HC97 1/20 0.34
PGR P06401 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530726 0.90 SNCA (0.38) SNCAESR2ESR1XDHTTR
SCHEMBL1852436 0.87 SNCA (0.48) SNCAESR2ESR1TTRALB
SCHEMBL27819091 0.81 TSHR (0.41) SNCAESR2ESR1XDHTTR
SCHEMBL1128865 0.81 TRPV4 (0.46) ESR2ESR1AR
SCHEMBL4353382 0.77 CA1 (0.53) ESR2MEN1KMT2ACA2AR
SCHEMBL9573876 0.77 SNCA (0.38) SNCAESR2ESR1TTRALB
SCHEMBL4972005 0.75 KDM4E (0.48) MEN1KMT2A
SCHEMBL5905817 0.75 AR (0.47) MEN1KMT2AARPGR
SCHEMBL4974071 0.75 ALDH1A1 (0.43) ESR2XDHMEN1KMT2A
SCHEMBL22977532 0.75 KDM4E (0.41) SNCAESR2ESR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5370119-A Device for measuring the pH of a target, method for using said device and applications thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM (FR) 1994-12-06 US claimed
EP-0764713-B1 Liquid crystal device and liquid crystal apparatus CANON KK (JP) 2001-07-18 EP disclosed
US-5858269-A COMPRISING A PAIR OF TRANSPARENT SUBSTRATES; TRANSPARENT ELECTRODES WITH A CHIRAL SMECTIC LIQUID CRYSTAL COMPOSITION DISPOSED BETWEEN SO AS TO ASSUME AT LEAST TWO OPTICALLY STABLE STATES; A POLYIMIDE AND MESOMORPHIC COMPOUND CANON KABUSHIKI KAISHA (JP) 1999-01-12 US disclosed
EP-0764713-A1 Liquid crystal device and liquid crystal apparatus CANON KABUSHIKI KAISHA (JP) 1997-03-26 EP disclosed
EP-0442499-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method using same CANON KK (JP) 1995-09-20 EP disclosed
US-5370119-A Device for measuring the pH of a target, method for using said device and applications thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM (FR) 1994-12-06 US disclosed
US-5217643-A Liquid crystal composition, liquid crystal device, display apparatus and display method using same CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
EP-0442499-A2 Liquid crystal composition, liquid crystal device, display apparatus and display method using same CANON KABUSHIKI KAISHA (JP) 1991-08-21 EP disclosed