SCHEMBL7765744

SCHEMBL7765744

NC(=O)CNC(=O)C(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
ALDH1A2 O94788 1/20 0.50
ALDH2 P05091 1/20 0.50
ALDH1A3 P47895 1/20 0.50
METAP1 P53582 1/20 0.35
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 1/20 0.32
PTGS2 P35354 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11738091 0.77 ALDH1A1 (0.54) ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A
SCHEMBL7773749 0.76 ALDH1A1 (0.58) ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A
SCHEMBL7346035 0.76
SCHEMBL7765732 0.75 ALDH1A1 (0.50) ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A
SCHEMBL7771108 0.75 METAP1 (0.35) ALDH1A1METAP1LMNAMAPTPTGS2
SCHEMBL3088751 0.75 ALDH1A1 (0.41) ALDH1A1METAP1KMT2ALMNAMAPT
SCHEMBL10959241 0.75 ALDH1A1 (0.50) ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A
SCHEMBL15623649 0.73 TERT (0.42) ALDH1A1METAP1LMNAMAPTPTGS2
SCHEMBL9214801 0.73 TERT (0.42) ALDH1A1METAP1LMNAMAPTPTGS2
SCHEMBL15808516 0.73 MEN1 (0.47) ALDH1A1METAP1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108496467-A The rice paddy seed and weed control methods handled through Herbicidal composition 三井化学AGRO株式会社 2018-09-07 CN disclosed
CN-105377012-B Rice seed treated with herbicidal composition and method for controlling weeds 三井化学AGRO株式会社 2018-04-27 CN disclosed
CN-106028810-A Pesticide composition for stem and leaf treatment 组合化学工业株式会社 2016-10-12 CN disclosed
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed
US-4623383-A HERBICIDES ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) 1986-11-18 US disclosed
US-4623383-A HERBICIDES ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) 1986-11-18 US disclosed
US-4623383-A HERBICIDES ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) 1986-11-18 US disclosed