Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773775 | 0.91 | SMN1; SMN2 (0.43) | TSHRPOLBSMN1; SMN2GAALMNA | |
| SCHEMBL4600179 | 0.79 | TSHR (0.52) | TSHRPOLBSMN1; SMN2GAALMNA | |
| SCHEMBL6388213 | 0.77 | TSHR (0.59) | TSHRPOLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL13629865 | 0.77 | POLB (0.41) | TSHRPOLBSMN1; SMN2GAALMNA | |
| SCHEMBL7769433 | 0.74 | TSHR (0.66) | TSHRPOLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7770891 | 0.72 | TSHR (0.58) | TSHRSMN1; SMN2GAALMNAKMT2A | |
| SCHEMBL9344572 | 0.70 | KMT2A (0.42) | TSHRPOLBLMNAKMT2AMEN1 | |
| SCHEMBL3221674 | 0.70 | GSK3A (0.58) | LMNAKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL5592121 | 0.69 | PLA2G10 (0.39) | TSHRPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL236431 | 0.69 | TSHR (0.56) | TSHRSMN1; SMN2GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |