Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 13/20 | 0.51 |
| ▸ | MMP13 | P45452 | 9/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236565 | 1.00 | MMP1 (0.53) | MMP1ADAM17MMP13ADAMTS4 | |
| SCHEMBL6237348 | 0.91 | MMP1 (0.62) | MMP1ADAM17MMP13 | |
| SCHEMBL6240294 | 0.85 | MMP1 (0.53) | MMP1ADAM17MMP13ADAMTS4 | |
| SCHEMBL6237873 | 0.84 | ADAM17 (0.61) | MMP1ADAM17MMP13 | |
| SCHEMBL6237731 | 0.83 | ADAM17 (0.50) | MMP1ADAM17MMP13ADAMTS4 | |
| SCHEMBL6237728 | 0.83 | ADAM17 (0.50) | MMP1ADAM17MMP13ADAMTS4 | |
| SCHEMBL6239549 | 0.80 | MMP1 (0.60) | MMP1ADAM17MMP13 | |
| SCHEMBL7761385 | 0.80 | MMP1 (0.60) | MMP1ADAM17MMP13 | |
| SCHEMBL7761414 | 0.80 | MMP1 (0.55) | MMP1ADAM17MMP13ADAMTS4 | |
| SCHEMBL6238546 | 0.80 | MMP1 (0.55) | MMP1ADAM17MMP13ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104412-A1 | TACE INHIBITORS | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009492-A1 | TACE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-02-24 | — | — | WO | disclosed |