Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765897 | 0.81 | HTT (0.39) | HTTCNR2 | |
| SCHEMBL9547614 | 0.80 | HTT (0.45) | HTTTSHRRAB9AHSD17B10CNR2 | |
| SCHEMBL7773594 | 0.79 | ALOX15 (0.44) | HTTTSHRLMNAHSD17B10 | |
| SCHEMBL7765955 | 0.77 | — | — | |
| SCHEMBL7771474 | 0.76 | SMN1; SMN2 (0.42) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL21680809 | 0.74 | HTT (0.46) | HTTTSHRLMNACYP3A4NFKB1 | |
| SCHEMBL4783072 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL7773645 | 0.73 | ALDH1A1 (0.48) | TSHRRAB9A | |
| SCHEMBL7769425 | 0.71 | EPHX1 (0.33) | RAB9A | |
| SCHEMBL965595 | 0.71 | HTT (0.48) | HTTTSHRLMNANFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |