Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 7/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7764855 | 0.96 | DNM1 (0.54) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL11670200 | 0.95 | DNM1 (0.48) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL11669841 | 0.95 | DNM1 (0.48) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL9648758 | 0.95 | DNM1 (0.48) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL11670679 | 0.91 | BBOX1 (0.46) | DNM1MEN1KMT2ATP53MAPK1 | |
| Malonic Acid SCHEMBL7763547 | 0.90 | DNM1 (0.54) | DNM1MEN1KMT2ATP53MAPK1 | |
| Acetic Acid SCHEMBL7764525 | 0.90 | DNM1 (0.57) | DNM1MEN1KMT2ATP53MAPK1 | |
| Miristalkonium Ion SCHEMBL17435024 | 0.87 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Cetalkonium SCHEMBL8149303 | 0.87 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 | |
| Cetalkonium SCHEMBL8148836 | 0.87 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |